2-Bromo-3-Methoxy Pyridine
2-bromo-3-methoxypyridine
CAS: 24100-18-3
Molecular Formula: C6H6BrNO
2-Bromo-3-Methoxy Pyridine - Names and Identifiers
| Name | 2-bromo-3-methoxypyridine |
| Synonyms | AKOS BBS-00006021 TIMTEC-BB SBB005633 BROMO-3-METHOXYPYRIDINE 2-BROMO-3-METHOXYPYRIDI 2-bromo-3-methoxypyridine 2-BROMO-3-METHOXYPYRIDINE 2-Bromo-3-Methoxy Pyridine Pyridine,2-bromo-3-methoxy- |
| CAS | 24100-18-3 |
| EINECS | 246-017-9 |
| InChI | InChI=1/C6H6BrNO/c1-9-5-3-2-4-8-6(5)7/h2-4H,1H3 |
2-Bromo-3-Methoxy Pyridine - Physico-chemical Properties
| Molecular Formula | C6H6BrNO |
| Molar Mass | 188.02 |
| Density | 1.530±0.06 g/cm3(Predicted) |
| Melting Point | 45-49 °C (lit.) |
| Boling Point | 233.4±20.0 °C(Predicted) |
| Flash Point | >230°F |
| Solubility | Dichloromethane |
| Vapor Presure | 0.0852mmHg at 25°C |
| Appearance | Crystalline Powder |
| Color | White to cream |
| pKa | -0.51±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.542 |
| MDL | MFCD01570896 |
2-Bromo-3-Methoxy Pyridine - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
| WGK Germany | 3 |
| HS Code | 29333990 |
2-Bromo-3-Methoxy Pyridine - Introduction
2-bromo-3-methoxypyridine is an organic compound with the chemical formula C6H6BrNO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless liquid
-Solubility: Soluble in anhydrous ethanol and Ether solvents
-Boiling point: 167-169 ° C
-Density: 1.568 g/mL
Use:
2-bromo-3-methoxypyridine has certain applications in the field of chemistry:
-As an intermediate: can be used to synthesize other organic compounds, such as drugs, pesticides and dyes.
-Organic synthesis: It can participate in a variety of different reactions, such as electrophilic substitution reactions, condensation reactions, etc.
Method:
2-bromo-3-methoxypyridine synthesis methods are mainly the following:
1. By the reaction of 3-methoxypyridine and bromine: 3-methoxypyridine is reacted with bromine and heated under alkaline conditions to obtain the product 2-bromo-3-methoxypyridine.
2. By the reaction of pyridine and 2-Bromo methyl ether: pyridine and 2-Bromo methyl ether reaction, under appropriate conditions for heating or using a catalyst to generate the desired product.
Safety Information:
The security of 2-bromo-3-methoxypyridine needs attention. The following are some security tips:
-Avoid inhalation, contact with skin, or entering eyes. Wear appropriate protective equipment such as gloves, goggles and face shields during use.
-When storing, it should be placed in a well-ventilated place, away from fire and oxidizing agents.
-Read the relevant safety data sheet carefully before use and use it in accordance with the correct operating procedures.
Nature:
-Appearance: colorless liquid
-Solubility: Soluble in anhydrous ethanol and Ether solvents
-Boiling point: 167-169 ° C
-Density: 1.568 g/mL
Use:
2-bromo-3-methoxypyridine has certain applications in the field of chemistry:
-As an intermediate: can be used to synthesize other organic compounds, such as drugs, pesticides and dyes.
-Organic synthesis: It can participate in a variety of different reactions, such as electrophilic substitution reactions, condensation reactions, etc.
Method:
2-bromo-3-methoxypyridine synthesis methods are mainly the following:
1. By the reaction of 3-methoxypyridine and bromine: 3-methoxypyridine is reacted with bromine and heated under alkaline conditions to obtain the product 2-bromo-3-methoxypyridine.
2. By the reaction of pyridine and 2-Bromo methyl ether: pyridine and 2-Bromo methyl ether reaction, under appropriate conditions for heating or using a catalyst to generate the desired product.
Safety Information:
The security of 2-bromo-3-methoxypyridine needs attention. The following are some security tips:
-Avoid inhalation, contact with skin, or entering eyes. Wear appropriate protective equipment such as gloves, goggles and face shields during use.
-When storing, it should be placed in a well-ventilated place, away from fire and oxidizing agents.
-Read the relevant safety data sheet carefully before use and use it in accordance with the correct operating procedures.
Last Update：2024-04-09 02:00:44
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